NOVEMBER 4, 2016 • PHILADELPHIA • DREXEL UNIVERSITY

SPONSORED BY

NuVasive

 

Globus

PROGRAM

Drexel University
Mitchell Auditorium, Bossone Research Center
3120 Market Street, Philadelphia, PA 19104

 

DOWNLOAD a copy of the complete schedule with abstracts

 

7:30 – 9:00 A.M.

Poster Setup

8:00 – 9:00 A.M.

Registration and Breakfast

9:00 – 9:05 A.M.

Welcome

SESSION ONE -

RESEARCH IN INDUSTRY

Moderators: Michele Marcolongo, Irving Shapiro

9:05 – 9:20 A.M.

KEYNOTE TALK:
Growth Modulation of The Spine for Treating Scoliosis: Establishing the Safety and Efficacy of a New Treatment Paradigm
Brian S. Snyder

9:20 – 9:32 A.M.

Research and Innovation in Spine: A Perspective from Industry [NuVasive, Inc.]
Kyle Malone

9:32 – 9:44 A.M.

Closing the Gap of Translational Medicine in Spine: A Practical Framework for R&D [Globus Medical, Inc.]
Brandon Bucklen

9:44 – 9:56 A.M.

Preclinical Development of an Allogeneic Cell Therapy [DiscGenics, Inc.]
Lara Ionescu Silverman

9:56 – 10:15 A.M.

Question and Answer Session

10:15 – 10:30 A.M.

Coffee Break and Poster Session / Poster presenters available to answer questions 

SESSION TWO -

DEVELOPMENT AND HOMEOSTASIS

Moderators: Makarand Risbud, James Iatridis

10:30 – 10:45 A.M.

KEYNOTE TALK:
Sex/Gender and Chronic Pain: The Role of TNF
John R. Bethea

10:45 – 10:53 A.M.

Rho Pathway Activation Protects Against Inflammatory Induced Alterations in Biomechanics of Cells from the Nucleus Pulposus in a Myosin-II Contractility Dependent Mechanism
Timothy Jacobsen

10:53 – 11:01 A.M. TonEBP Maintains Inflammatory Gene Expression in the Hyperosmotic Nucleus Pulposus
Zariel Johnson

11:01 – 11:09 A.M.

TGF-β1 Induces a Contractile CD146+ Phenotype of Human Annulus Fibrosus Cells with Affinity to Collagen Scaffold for Annulus Fibrosus Repair
Rose G. Long

11:09 – 11:20 A.M.

Question and Answer Session

11:20 – 11:28 A.M.

Effects of Hypoxia and TGF-β Exposure during Monolayer Expansion on the Survival and Matrix Producing Capacity of Mesenchymal Stem Cells
Sun H. Peck

11:28 – 11:36 A.M.

HIF-1α-Carbonic Anhydrase Axis Controls Acid-Base Metabolism in Hypoxic Nucleus Pulposus Cells
Elizabeth S. Silagi

11:36 – 11:44 A.M.

Region-Specific Orthotropic Growth of the Pediatric Thoracic Spine through Finite Element Methods
John P. Dougherty

11:44 A.M. – Noon

Question and Answer Session

12:00 – 1:15 P.M.

Boxed Lunch and Poster Session
Poster presenters available to answer questions: 12:15 – 1:15 PM

SESSION THREE

PATHOPHYSIOLOGY

Moderators: Neil Malhotra, Dawn Elliott

1:15 – 1:30 P.M.

KEYNOTE TALK:
Growth Modulation Strategies to Treat Skeletally Immature Scoliosis
Amer Samdani

1:30 – 1:38 P.M.

Normalcy of Vertebral Morphology for Lenke-types 1, 2, and 5 Two-Years Following Spinal Fusion Surgery
James R. Peters

1:38 – 1:46 P.M.

Disc Height Loss, But Not Pro-Inflammatory Cytokine or Substance P Expression, Predicts Intervertebral Disc Degeneration-Related Pain in a Rat Model
Thomas W. Evashwick-Rogler

1:46 – 1:54 P.M.

Does Baseline Sagittal Balance Influence the Surgical Outcomes of Patients with Cervical Myelopathy?
Paul Millhouse

1:54 – 2:07 P.M.

Question and Answer Session

2:07 – 2:15 P.M.

High Mobility Group Box-1 Promotes Pro-inflammatory Signaling in Human Nucleus Pulposus Cells via Toll-Like Receptor 4
Bhranti S. Shah

2:15 – 2:23 P.M.

Neuropeptide Y Promoter Variant Correlates with Decreased Pain at Baseline in Older Adults with Mild to Moderate Lumbar Spinal Stenosis but a Blunted Functional Response to Exercise-based Treatment Protocols
Sara Ernst

2:23 - 2:31 P.M.

Identification of the Compositional Traits and Permeabilities of the Cartilage Endplate that are Required for Nutrient Transport and Disc Cell Survival
Jason Wong

2:31 – 2:39 P.M.

Changes in Muscle Mass and Bone Morphology of the Spine and Lower Limb after Spinal Chord Injury and Treadmill Training
Shania Shaji

2:39 – 2:50 P.M. Question and Answer Session
2:50 – 3:30 P.M.

Coffee Break and Poster Session / Poster presenters available to answer questions

SESSION FOUR –

DIAGNOSTICS AND THERAPEUTICS

Moderators: Lachlan Smith, Thomas Schaer 

3:30 – 3:45 P.M.

KEYNOTE TALK:
Imaging Back Pain
Daniel H. Cortes

3:45 – 3:53 P.M.

Load-sharing of the Intervertebral Discs During Standing Determined by Open-Upright Magnetic Resonance Imaging
Christian I. Weber

3:53 – 4:01 P.M.

Predicting Intradiscal Pressure in the Cervical Spine Based on Disc Height
Forbes E. Howington

4:01 – 4:09 P.M.

Development of an In Vivo Model of Neonatal Intervertebral Disc Injury and Regeneration
Olivia M. Torre

4:09 – 4:20 P.M. Question and Answer Session

4:20 – 4:28 P.M.

Engineered Endplates Enhance the In Vivo Performance of a Replacement Disc-Like Angle Ply Structure (DAPS)
Sarah E. Gullbrand

4:28 – 4:36 P.M.

FLASH MRI for Potential Clinical Diagnostics of Cartilaginous Endplate Discontinuities
Kyle Meadows

4:36 – 4:44 P.M.

Injectable Scaffolds with Bioadhesive Properties for the Regeneration of the Annulus Fibrosus and Nucleus Pulposus of the Intervertebral Disc
Thomas Christiani

4:44 – 4:52 P.M.

Injectable Cellulosic Hydrogels as Nucleus Pulposus Replacements: Assessment of Herniation Risk, Fatigue Behavior, and In Vivo Biocompatibility
Huizi Anna Lin

4:52 – 5:05 P.M.

Question and Answer Session 

5:15 – 5:30 P.M.

Concluding Remarks and Presentation of Awards 

5:30 – 7:00 P.M.

Networking Reception and Posters 

 

JEFFERSON MEDICAL SCHOOL • UNIVERSITY OF PENNSYLVANIA • DREXEL UNIVERSITY
UNIVERSITY OF DELAWARE • MOUNT SINAI • PENNSYLVANIA STATE UNIVERSITY